Fringe - All About Hair

This blog explores topics in 'Trichology' (the orthodox sciences of human hair). We welcome you either as an interested visitor or a prospective student seeking to study trichology to share your comments and experience. As the archives continue to accumulate, probably at some point they will become a useful reference for all. This hair loss forum may help you to grow hair too!


Another guardian against alopecia areata?


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Linear non scarring alopecia of the scalp: A rare manifestation of lupus panniculitis

Indian Journal of Dermatology

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Serum vitamin D3 level in patients with female pattern hair loss

Mahnaz Banihashemi, Yalda Nahidi, Naser Tayyebi Meibodi, Lida Jarahi, Mojgan Dolatkhah

International Journal of Trichology 2016 8(3):116-120

Background: Female pattern hair loss (FPHL) is the most common cause of alopecia in women, characterized by diffuse nonscarring hair loss in frontal, central, and parietal areas of the scalp. Pathophysiology of FPHL is still not well known, and it is probably a multifactorial genetic trait. FPHL is also observed in women without increased androgen levels, which raises the likelihood of androgen-independent mechanisms and explains the lack of response to antiandrogen treatments in some patients. Vitamin D is a factor that has recently been considered in dealing with these patients. The purpose of this study was to evaluate the serum levels of Vitamin D in patients with FPHL and compare it with healthy controls. Methods: In this case-control study, 45 women with FPHL were evaluated as well as the same number of healthy women matched for age, hours spent under sunlight per day, and body mass index. Serum 25(OH) D3 level was measured using ELISA. Results: 60% of FPHL patients were in 15-30 years old age group with the mean standard deviation (SD) age of 29.11 (7.30) years. In the majority of patients (66.7%), severity of hair loss was Ludwig I. Mean (SD) serum Vitamin D3 level in patient and control group was 13.45 (8.40) and 17.16 (8.96), respectively. T-test showed a significant difference between the two groups in terms of Vitamin D3 serum levels (P = 0.04). Conclusions: This study indicated the correlation between the incidence of FPHL and decreased serum levels of Vitamin D3. It is recommended to evaluate serum Vitamin D3 levels as well as other hormone assays in these patients.

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What are the dietary recommendations for hair growth

Many dietary supplements have entered the market to support increased hair growth

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Cocking the eyebrows to find the missing hairline in frontal fibrosing alopecia: A useful clinical maneuver

Frontal fibrosing alopecia is a type of lymphocyte-mediated cicatricial alopecia with a unique pattern of bandlike hair loss along the frontal hairline and loss of eyebrows. Determining the extent of hairline recession and identifying the location of the “missing” or original hairline can be challenging but is critical for initial assessments and for gauging response to treatment. Classically, the sharp contrast between the photodamaged skin on the forehead and the formerly photoprotected frontal hairline of the scalp has been used to delineate the hairline, but this photodamage is not seen in all patients.

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Effect of fibroblast growth factor 2 containing dalteparin protamine nanoparticles on hair growth

Spiked Hair
Spiked Hair (Photo credit: Wikipedia)
By:Takabayashi Y, Nambu M, Ishihara M, Kuwabara M, Fukuda K, Nakamura S, Hattori H, Kiyosawa T

Although treatments for alopecia are in high demand, not all treatments are safe and reliable. Dalteparin/protamine nanoparticles (D/P NPs) can effectively carry growth factors (GFs) such as fibroblast GF (FGF)-2. The purpose of this study was to identify the effects of FGF-2-containing D/P NPs (FGF-2&D/P NPs) on hair growth.

 In this study, the participants were 12 volunteers with thin hair. One milliliter of FGF-2 (100 ng/mL) and D/P NPs (56 μg/mL) was applied and massaged on the skin of the scalp by the participants twice a day. They were evaluated for 6 months. Participants were photographed using a digital camera for general observation and a hair diagnosis system for measuring hair diameter.

Results:
The mean diameter of the hairs was significantly higher following the application of FGF-2&D/P NPs for 6 months. Objective improvements in thin hair were observed in two cases. Nine participants experienced greater bounce and hair resilience.

Conclusion: The transdermal application of FGF-2&D/P NPs to the scalp can be used as a new treatment for alopecia.

Read the full article @ Dovepress.

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The benefits of dry shampoos


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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.

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Bell Raj Eapen
Hamilton, ON
Canada