Fringe - All About Hair

This blog explores topics in 'Trichology' (the orthodox sciences of human hair). We welcome you either as an interested visitor or a prospective student seeking to study trichology to share your comments and experience. As the archives continue to accumulate, probably at some point they will become a useful reference for all. This hair loss forum may help you to grow hair too!


Effect of fibroblast growth factor 2 containing dalteparin protamine nanoparticles on hair growth

Spiked Hair
Spiked Hair (Photo credit: Wikipedia)
By:Takabayashi Y, Nambu M, Ishihara M, Kuwabara M, Fukuda K, Nakamura S, Hattori H, Kiyosawa T

Although treatments for alopecia are in high demand, not all treatments are safe and reliable. Dalteparin/protamine nanoparticles (D/P NPs) can effectively carry growth factors (GFs) such as fibroblast GF (FGF)-2. The purpose of this study was to identify the effects of FGF-2-containing D/P NPs (FGF-2&D/P NPs) on hair growth.

 In this study, the participants were 12 volunteers with thin hair. One milliliter of FGF-2 (100 ng/mL) and D/P NPs (56 μg/mL) was applied and massaged on the skin of the scalp by the participants twice a day. They were evaluated for 6 months. Participants were photographed using a digital camera for general observation and a hair diagnosis system for measuring hair diameter.

Results:
The mean diameter of the hairs was significantly higher following the application of FGF-2&D/P NPs for 6 months. Objective improvements in thin hair were observed in two cases. Nine participants experienced greater bounce and hair resilience.

Conclusion: The transdermal application of FGF-2&D/P NPs to the scalp can be used as a new treatment for alopecia.

Read the full article @ Dovepress.

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Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers

Experimental Dermatology

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Skin with hair follicles and glands grown in lab

Using stem cells, scientists grew complex 3D skin tissue - complete with hair follicles and sebaceous glands - that connected with nerves and muscle fibers when implanted in mice.

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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.

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Bell Raj Eapen
Hamilton, ON
Canada